Detomidine (Domosedan)– a new sedative and analegsic
نویسندگان
چکیده
منابع مشابه
The sedative and analgesic effects of detomidine-butorphanol and detomidine alone in donkeys.
Butorphanol and detomidine constitute an effective combination for sedation and analgesia in horses. This trial was undertaken to assess the effectiveness of this combination in donkeys. The detomidine and butorphanol were given intravenously one after the other. A dose of 10 microg/kg of detomidine and 25 microg/kg of butorphanol was used. Sedation is easily extended by additional doses of but...
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چکیده ندارد.
15 صفحه اولAccidental poisoning with detomidine and butorphanol.
This is a case report concerning a veterinarian who spilled detomidine and butorphanol on dermatitic hands while sedating a horse. This resulted in acute poisoning from which the patient spontaneously recovered with supportive management. Veterinarians often suffer from occupational dermatitis and handle strong sedatives with no gloves while working around unpredictable animals. Thus, this grou...
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BACKGROUND Using gentler endoscopes and improved sedation, great strides have been made in enhancing patients' comfort and acceptance of endoscopic procedures. Because morbidity and mortality have been associated with benzodiazepines in endoscopic sedation, safer alternatives were sought. Propofol (2,6-diisopropylphenol), a rapid and short-acting anesthetic, initially used in the 1980's for gen...
متن کاملDexmedetomidine: Sedative and Neuroprotective Mechanisms of Action and New Developments
Dexmedetomidine, the D-enantiomer of medetomidine, is among the most potent sedative drugs known. It is also one of the best understood in terms of its molecular and cellular mechanisms. Its sedative (and probably its neuroprotective) effects are mediated by subtype A of the α2 adrenergic receptor, a G-protein-coupled receptor. Acting as an agonist at this receptor, dexmedetomidine causes numer...
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ژورنال
عنوان ژورنال: Pferdeheilkunde Equine Medicine
سال: 1986
ISSN: 0177-7726
DOI: 10.21836/pem19860401